December  2016

The Newsletter intends, in this space, to give our readers an overview of the scientific production conducted at the Faculty of Medicine and at University of Lisbon/Santa Maria Hospital/ Institute of Molecular Medicine.

To access full-text articles, you must be connected to the FMUL network. The database used is the ISI-Web of Knowledge.

 

 

 

Radiolabeled block copolymer micelles for image-guided drug delivery

Ribeiro, E (Ribeiro, Elisabete) ; Alho, I (Alho, Irina) ; Marques, F (Marques, Fernanda) ; Gano, L (Gano, Lurdes) ; Correia, I (Correia, Isabel) ; Correia, JDG (Correia, João D. G.) ; Casimiro, S (Casimiro, Sandra) ; Costa, L (Costa, Luís) ; Santos, I (Santos, Isabel) ; Fernandes, C (Fernandes, Célia)

INTERNATIONAL JOURNAL OF PHARMACEUTICS. Volume: 515. Edição: 1-2. pp. 692-701. DOI: 10.1016/j.ijpharm.2016.11.004. dezembro 2016

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Naa50/San-dependent N-terminal acetylation of Scc1 is potentially important for sister chromatid cohesion

Ribeiro, AL (Ribeiro, Ana Luísa) ; Silva, RD (Silva, Rui D.) ; Foyn, H (Foyn, Havard) ; Tiago, MN (Tiago, Margarida N.) ; Rathore, OS (Rathore, Om Singh) ; Arnesen, T (Arnesen, Thomas) ; Martinho, RG (Martinho, Rui Gonçalo)

SCIENTIFIC REPORTS. Volume: 6. DOI: 10.1038/srep39118. dezembro 2016

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Adolescent’s subjective perceptions of chronic disease and related psychosocial factors: highlights from an outpatient context study

Santos, T (Santos, Teresa) ; de Matos, MG (de Matos, Margarida Gaspar) ; Marques, A (Marques, Adilson) ; Simões, C (Simões, Celeste) ; Leal, I (Leal, Isabel) ; Machado, MD (Machado, Maria do Céu)

BMC PEDIATRICS. Volume: 16. DOI: 10.1186/s12887-016-0748-x. dezembro 2016

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Integrated (epi)-Genomic Analyses Identify Subgroup-Specific Therapeutic Targets in CNS Rhabdoid Tumors

Torchia, J (Torchia, Jonathon) ; Golbourn, B (Golbourn, Brian) ; Feng, SR (Feng, Shengrui) [et al.]

CANCER CELL. Volume: 30. Edição: 6. pp. 891-908. DOI: 10.1016/j.ccell.2016.11.003

dezembro 2016

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Computational fluid dynamics assisted characterization of parafoveal hemodynamics in normal and diabetic eyes using adaptive optics scanning laser ophthalmoscopy

Lu, Y (Lu, Yang) ; Bernabeu, MO (Bernabeu, Miguel O.) ; Lammer, J (Lammer, Jan) ; Cai, CC (Cai, Charles C.) ; Jones, ML (Jones, Martin L.) ; Franco, CA (Franco, Cláudio A.) ; Aiello, LP (Aiello, Lloyd Paul) ; Sun, JK (Sun, Jennifer K.)

BIOMEDICAL OPTICS EXPRESS. Volume: 7. Edição: 12. pp. 4958-4973

DOI: 10.1364/BOE.7.004958. dezembro 2016

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RHAPSODY – Internet-based support for caregivers of people with young onset dementia: program design and methods of a pilot study

Kurz, A (Kurz, Alexander) ; Bakker, C (Bakker, Christian) ; Bohm, M (Boehm, Markus) ; Diehl-Schmid, J (Diehl-Schmid, Janine) ; Dubois, B (Dubois, Bruno) ; Ferreira, C (Ferreira, Catarina) ; Gage, H (Gage, Heather) ; Graff, C (Graff, Caroline) ; Hergueta, T (Hergueta, Thierry) ; Jansen, S (Jansen, Sabine) [et al.]

Autor(es) grupo: RHAPSODY Study Grp. INTERNATIONAL PSYCHOGERIATRICS

Volume: 28. Edição: 12. pp. 2091-2099. DOI: 10.1017/S1041610216001186. dezembro 2016

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Interventions for age-related diseases: Shifting the paradigm

Figueira, I (Figueira, Inês) ; Fernandes, Adelaide ; Djordjevic, AM (Djordjevic, Aleksandra Mladenovic) ; Lopez-Contreras, A (Lopez-Contreras, Andres) ; Henriques, CM (Henriques, Catarina M.) ; Selman, C (Selman, Colin) ; Ferreiro, E (Ferreiro, Elisabete) ; Gonos, ES (Gonos, Efstathios S.) ; Trejo, JL (Luís Trejo, José) ; Misra, J (Misra, Juhi) ; Rasmussen, LJ (Rasmussen, Lene Juel) ; Xapelli, S (Xapelli, Sara) ; Ellam, T (Ellam, Timothy) ; Bellantuono, I (Bellantuono, Ilaria)

MECHANISMS OF AGEING AND DEVELOPMENT. Volume: 160. pp. 69-92

DOI: 10.1016/j.mad.2016.09.009. dezembro 2016

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Unravelling Malaria Antigen Binding to Antibody-Gold Nanoparticle Conjugates

Cavadas, MAS (Cavadas, Miguel A. S.) ; Monopoli, MP (Monopoli, Marco P.) ; Cunha, CSE (Sá e Cunha, Cláudia) ; Prudêncio, M (Prudêncio, Miguel) ; Pereira, E (Pereira, Eulália) ; Lynch, I (Lynch, Iseult) ; Dawson, KA (Dawson, Kenneth A.) ; Franco, R (Franco, Ricardo)

PARTICLE & PARTICLE SYSTEMS CHARACTERIZATION. Volume: 33. Edição: 12. pp. 906-915. DOI: 10.1002/ppsc.201600187. dezembro 2016

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Brown Tumors in Secondary Hyperparathyroidism in a Patient With Lupus Nephritis

Fernandes, S (Fernandes, Silvia) ; Almeida, P (Almeida, Paulo) ; Melo-Gomes, J (Melo-Gomes, José) ; Romeu, JC (Romeu, José Carlos).

JCR-JOURNAL OF CLINICAL RHEUMATOLOGY. Volume: 22. Edição: 8. pp. 438-439

DOI: 10.1097/RHU.0000000000000397. dezembro 2016

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Plasmid-Borne Antimicrobial Resistance of Staphylococcus aureus Isolated in a Hospital in Lisbon, Portugal

Costa, SS (Costa, Sofia Santos) ; Palma, C (Palma, Cláudia) ; Kadlec, K (Kadlec, Kristina) ; Fessler, AT (Fessler, Andrea T.) ; Viveiros, M (Viveiros, Miguel) ; Melo-Cristino, J (Melo-Cristino, José) ; Schwarz, S (Schwarz, Stefan) ; Couto, I (Couto, Isabel)

MICROBIAL DRUG RESISTANCE. Volume: 22. Edição: 8. pp. 617-626

DOI: 10.1089/mdr.2015.0352. dezembro 2016

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Non-Canonical Expression Patterns and Evolutionary Rates of Sex-Biased Genes in a Seasonal Fish

Machado, MP (Machado, Miguel P.) ; Matos, I (Matos, Isa) ; Grosso, AR (Grosso, Ana R.) ; Schartl, M (Schartl, Manfred) ; Coelho, MM (Coelho, Maria M.)

MOLECULAR REPRODUCTION AND DEVELOPMENT. Volume: 83.

Edição: 12. pp. 1102-1115. DOI: 10.1002/mrd.22752. dezembro 2016

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Cerebral venous thrombosis

Ferro, JM (Ferro, José Manuel) ; Canhão, P (Canhão, Patricia) ; de Sousa, DA (de Sousa, Diana Aguiar).

PRESSE MEDICALE. Volume: 45. Edição: 12. pp. E429-E450. Parte: 2. DOI: 10.1016/j.lpm.2016.10.007. dezembro 2016

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Delta One T Cells for Immunotherapy of Chronic Lymphocytic Leukemia: Clinical-Grade Expansion/Differentiation and Preclinical Proof of Concept

Almeida, AR (Almeida, Afonso R.) ; Correia, DV (Correia, Daniel V.) ; Fernandes-Platzgummer, A (Fernandes-Platzgummer, Ana) ; da Silva, CL (da Silva, Cláudia L.) ; da Silva, MG (da Silva, Maria Gomes) ; Anjos, DR (Anjos, Diogo Remechido) ; Silva-Santos, B (Silva-Santos, Bruno)

CLINICAL CANCER RESEARCH. Volume: 22. Edição: 23. pp. 5795-5804

DOI: 10.1158/1078-0432.CCR-16-0597. dezembro 2016

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Palmar rash in a teenager: more than meets the eye

Sousa, R (Sousa, Rodrigo) ; Contreiras, M (Contreiras, Marta) ; Lima, SC (Lima, Sofia Costa) ; Oom, P (Oom, Paulo).

CLINICAL CASE REPORTS. Volume: 4. Edição: 12. pp. 1203-1204

DOI: 10.1002/ccr3.713. dezembro 2016

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Unwitnessed head trauma: the bamboo did it

Sousa, R (Sousa, Rodrigo) ; Luz, A (Luz, Ângela) ; Abecasis, F (Abecasis, Francisco) ; Vieira, M (Vieira, Marisa)

CLINICAL CASE REPORTS. Volume: 4. Edição: 12. pp. 1207-1208

DOI: 10.1002/ccr3.724. dezembro 2016

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Cognitive reserve moderates long-term cognitive and functional outcome in cerebral small vessel disease

Jokinen, H (Jokinen, Hanna) ; Melkas, S (Melkas, Susanna) ; Madureira, S (Madureira, Sofia) ; Verdelho, Ana) ; Ferro, JM (Ferro, José M.) ; Fazekas, F (Fazekas, Franz) ; Schmidt, R (Schmidt, Reinhold) ; Scheltens, P (Scheltens, Philip) ; Barkhof, F (Barkhof, Frederik) ; Wardlaw, JM (Wardlaw, Joanna M.) ; Inzitari, D (Inzitari, Domenico) ; Pantoni, L (Pantoni, Leonardo) ; Erkinjuntti, T (Erkinjuntti, Timo)

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY. Volume: 87

Edição: 12. pp. 1296-1302. DOI: 10.1136/jnnp-2016-313914. dezembro 2016

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Patisiran ph 2 open-label extension study in familial amyloidotic polyneuropathy

Schmidt, H (Schmidt, Hartmut) ; Adams, D (Adams, David) ; Coelho, T (Coelho, Teresa) ; Conceição, I (Conceição, Isabel) ; Waddington-Cruz, M (Waddington-Cruz, Márcia) ; Buades, J (Buades, Juan) ; Campistol, J (Campistol, Josep) ; Pouget, J (Pouget, Jean) ; Gollob, J (Gollob, Jared) ; Suhr, O (Suhr, Ole).

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY. Volume: 87.

Edição: 12. DOI: 10.1136/jnnp-2016-315106.29. dezembro 2016

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Antibody-drug conjugates: The missing link

Rodrigues, T (Rodrigues, Tiago) ; Bernardes, GJL (Bernardes, Gonçalo J. L.)

NATURE CHEMISTRY. Volume: 8. Edição: 12. pp. 1088-1090

DOI: 10.1038/nchem.2685. dezembro 2016

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Low-grade epilepsy-associated neuroepithelial tumours – the 2016 WHO classification

Blumcke, I (Bluemcke, Ingmar) ; Aronica, E (Aronica, Eleonord) ; Becker, A (Becker, Albert) ; Capper, D (Capper, David) ; Coras, R (Coras, Roland) ; Honavar, M (Honavar, Mrinalini) ; Jacques, TS (Jacques, Thomas S.) ; Kobow, K (Kobow, Katja) ; Miyata, H (Miyata, Hajime)[ 7 ] ; Muhlebner, A (Muhlebner, Angelika) Pimentel, J (Pimentel, José) ; Soylemezoglu, F (Soylemezoglu, Figen) ; Thom, M (Thom, Maria)

NATURE REVIEWS NEUROLOGY. Volume: 12. Edição: 12. pp. 732-740

DOI: 10.1038/nrneurol.2016.173. dezembro 2016

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Report of the 4th European Zebrafish Principal Investigator Meeting

Lopes, SS (Lopes, Susana S.) ; Distel, M (Distel, Martin) ; Linker, C (Linker, Cláudia) ; Fior, R (Fior, Rita) ; Monteiro, R (Monteiro, Rui) ; Bianco, IH (Bianco, Isaac H.) ; Português, R (Português, Ruben) ; Strahle, U (Straehle, Uwe) ; Saude, L (Saude, Leonor)

ZEBRAFISH. Volume: 13. Edição: 6. pp. 590-595. DOI: 10.1089/zeb.2016.1364

dezembro 2016

abstract

Differentiating biosimilarity and comparability in biotherapeutics

Azevedo, V (Azevedo, Valderílio) ; Hassett, B (Hassett, Brian) ; Fonseca, JE (Fonseca, João Eurico) ; Atsumi, T (Atsumi, Tatsuya) ; Coindreau, J (Coindreau, Javier) ; Jacobs, I (Jacobs, Ira) ; Mahgoub, E (Mahgoub, Ehab) ; O’Brien, J (O’Brien, Julie) ; Singh, E (Singh, Ena) ; Vicik, S (Vicik, Steven) ; Fitzpatrick, B (Fitzpatrick, Brian)

CLINICAL RHEUMATOLOGY. Volume: 35. Edição: 12. pp. 2877-2886

DOI: 10.1007/s10067-016-3427-2. dezembro 2016

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New insights into the immunopathogenesis of systemic lupus erythematosus

Tsokos, GC (Tsokos, George C.) ; Lo, MS (Lo, Mindy S.) ; Reis, PC (Reis, Patrícia Costa) ; Sullivan, KE (Sullivan, Kathleen E.)

NATURE REVIEWS RHEUMATOLOGY. Volume: 12. Edição: 12. pp. 716-730

DOI: 10.1038/nrrheum.2016.186. dezembro 2016

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In response to Inferior peduncle lesion presenting with bilaterally impaired vestibular responses to horizontal and posterior head impulses

Sousa, R (Sousa, Rita) ; Maia, FZE (Zuma e Maia, Francisco) ; Luís, L (Luís, Leonel)

LARYNGOSCOPE. Volume: 126. Edição: 12. pp. E424-E424

DOI: 10.1002/lary.25984. dezembro 2016

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Phenotype and Genotype in 52 Patients with Rubinstein-Taybi Syndrome Caused by EP300 Mutations

Fergelot, P (Fergelot, Patricia)[ 1,2 ] ; Van Belzen, M (Van Belzen, Martine)[ 3 ] ; Van Gils, J (Van Gils, Julien)[et al.]

AMERICAN JOURNAL OF MEDICAL GENETICS PART A. Volume: 170. Edição: 12.

3082. 3069-3082. DOI: 10.1002/ajmg.a.37940. dezembro 2016

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Similar hemodynamic decongestion with vasodilators and inotropes: systematic review, meta-analysis, and meta-regression of 35 studies on acute heart failure

Ishihara, S (Ishihara, Shiro)] ; Gayat, E (Gayat, Etienne) ; Sato, N (Sato, Naoki) ; Arrigo, M (Arrigo, Mattia) ; Laribi, S (Laribi, Said) ; Legrand, M (Legrand, Matthieu) ; Plácido, R (Plácido, Rui) ; Manivet, P (Manivet, Philippe) ; Cohen-Solal, A (Cohen-Solal, Alain) ; Abraham, WT (Abraham, William T.) ; Jessup, M (Jessup, Mariell) ; Mebazaa, A (Mebazaa, Alexandre)

CLINICAL RESEARCH IN CARDIOLOGY. Volume: 105. Edição: 12. pp. 971-980

DOI: 10.1007/s00392-016-1009-6. dezembro 2016

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Pain modulation from the brain during diabetic neuropathy: Uncovering the role of the rostroventromedial medulla

Silva, M (Silva, Marta) ; Costa-Pereira, JT (Costa-Pereira, José Tiago) ; Martins, D (Martins, Daniel) ; Tavares, I (Tavares, Isaura)

NEUROBIOLOGY OF DISEASE. Volume: 96. Páginas: 346-356. DOI: 10.1016/j.nbd.2016.10.002. Publicado: DEC 2016

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Genetic Disruption of Circadian Rhythms in the Suprachiasmatic Nucleus Causes Helplessness, Behavioral Despair, and Anxiety-like Behavior in Mice

Landgraf, D (Landgraf, Dominic) ; Long, JE (Long, Jaimie E.) ; Proulx, CD (Proulx, Christophe D.) ; Barandas, R (Barandas, Rita) ; Malinow, R (Malinow, Roberto)[ 4 ] ; Welsh, DK (Welsh, David K.)

BIOLOGICAL PSYCHIATRY. Volume: 80. Edição: 11. Páginas: 827-835

DOI: 10.1016/j.biopsych.2016.03.1050. dez 2016

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Subset-specific alterations in frequencies and functional signatures of gamma delta T cells in systemic sclerosis patients

Henriques, A (Henriques, Ana) ; Silva, C (Silva, Cláudia) ; Santiago, M (Santiago, Mariana) ; Henriques, MJ (Henriques, Maria João) ; Martinho, A (Martinho, António) ; Trindade, H (Trindade, Hélder) ; da Silva, JAP (Pereira da Silva, José António) ; Silva-Santos, B (Silva-Santos, Bruno) ; Paiva, A (Paiva, Artur)

INFLAMMATION RESEARCH. Volume: 65. Edição: 12. Páginas: 985-994

DOI: 10.1007/s00011-016-0982-6. dez 2016

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