A Newsletter pretende, neste espaço, dar aos seus leitores uma perspectiva da produção científica realizada na Faculdade de Medicina da Universidade de Lisboa / Hospital de Santa Maria / Instituto de Medicina Molecular.
Para aceder ao texto integral dos artigos, deverá estar conectado à rede da FMUL.
Outubro a Dezmbro de 2013.

1.
No association between VAPB mutations and familial or sporadic ALS in Sweden, Portugal and Iceland
Author(s): Ingre, Caroline ; Pinto, Susana ; Birve, Anna ; Press, Rayomand ; Danielsson, Olof ; de Carvalho, Mamede ; Gudmundsson, Gretar ; Andersen, Peter M.
Source: AMYOTROPHIC LATERAL SCLEROSIS AND FRONTOTEMPORAL DEGENERATION. Volume: 14 Issue: 7-8 Pages: 620-627 Published: DEC 2013
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2.
Patients’ access to biologics in rheumatoid arthritis: a comparison between Portugal and other European countries 
Author(s): Laires, PA ; Exposto, F ; Mesquita, R ; Martins, AP ; Cunha-Miranda, L ; Fonseca, JE.
Source: EUROPEAN JOURNAL OF HEALTH ECONOMICS. Volume: 14 Issue: 6 Pages: 875-885 DOI: 10.1007/s10198-012-0432-5 Published: DEC 2013
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3.
Affective temperaments and self-harm in adolescents: A cross-sectional study from a community sample 
Author(s): Guerreiro, Diogo Frasquilho ; Sampaio, Daniel ; Rihmer, Zoltan ; Gonda, Xenia ; Figueira, Maria Luísa
Source: JOURNAL OF AFFECTIVE DISORDERS Volume: 151 Issue: 3 Pages: 891-898 DOI: 10.1016/j.jad.2013.07.034 Published: DEC 2013
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4.
Clinical subtypes of severe bipolar mixed states 
Author(s): Perugi, Giulio ; Medda, Pierpaolo) ; Reis, João ; Rizzato, Salvatore ; Mariani, Michela Giorgi ; Mauri, Mauro)
Source: JOURNAL OF AFFECTIVE DISORDERS. Volume: 151 Issue: 3 Pages: 1076-1082 DOI: 10.1016/j.jad.2013.08.037 Published: DEC 2013
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5.
The burden of cyclothymia on alcohol dependence
Author(s): Pombo, Samuel ; Figueira, Maria Luísa ; da Costa, Nuno Félix ; Ismail, Fátima ; Yang, Guang ; Akiskal, Kareen; Akiskal, Hagop.
Source: JOURNAL OF AFFECTIVE DISORDERS. Volume: 151 Issue: 3 Pages: 1090-1096 DOI: 10.1016/j.jad.2013.09.002 Published: DEC 2013
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6.
Task Force Report: Scales for Screening and Evaluating Tremor Critique and Recommendations
Author(s): Elble, Rodger ; Bain, Peter ; Forjaz, Maria João [et al.] Source: MOVEMENT DISORDERS. Volume: 28 Issue: 13 Pages: 1793-1800 Published: NOV 2013
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7.
Underweight, overweight and obesity in paediatric dialysis and renal transplant patients
Author(s): Bonthuis, Marjolein ; van Stralen, Karlijn J ; Verrina, Enrico [et al.] Source: NEPHROLOGY DIALYSIS TRANSPLANTATION. Volume: 28 Supplement: 4 Pages: 195-204 Published: NOV 2013
Abstract

8.
Prospective clinical experience with research biopsies in breast cancer patients 
Author(s): Vaz-Luís, Inês ; Zeghibe, Catherine A. ; Frank, Elizabeth S [et al.] Source: BREAST CANCER RESEARCH AND TREATMENT Volume: 142 Issue: 1 Pages: 203-209 Published: NOV 2013
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9.
Harnessing the power of yeast to unravel the molecular basis of neurodegeneration
Author(s): Tenreiro, Sandra ; Munder, Matthias C.; Alberti, Simon ; Outeiro, Tiago F.
Source: JOURNAL OF NEUROCHEMISTRY Volume: 127 Issue: 4 Pages: 438-452 DOI: 10.1111/jnc.12271 Published: NOV 2013
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10.
Long-term effects of tafamidis for the treatment of transthyretin familial amyloid polyneuropathy
Author(s): Coelho, Teresa ; Maia, Luís F. ; da Silva, Ana Martins [et al.] Source: JOURNAL OF NEUROLOGY Volume: 260 Issue: 11 Pages: 2802-2814 DOI: 10.1007/s00415-013-7051-7 Published: NOV 2013
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11.
Recurrence patterns across medulloblastoma subgroups: an integrated clinical and molecular analysis 
Author(s): Ramaswamy, Vijay ; Remke, Marc ; Et, Eric Bouff ; Faria, [et al.] Source: LANCET ONCOLOGY Volume: 14 Issue: 12 Pages: 1200-1207 DOI: 10.1016/S1470-2045(13)70449-2 Published: NOV 2013
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12.
Mechanistic insights into the cytotoxicity and genotoxicity induced by glycidamide in human mammary cells
Author(s): Bandarra, Susana ; Fernandes, Ana S ; Magro, Inês ; [et al.].
Source: MUTAGENESIS Volume: 28 Issue: 6 Pages: 721-729 DOI: 10.1093/mutage/get052 Published: NOV 2013
Abstract

13.
rBPI(21) interacts with negative membranes endothermically promoting the formation of rigid multilamellar structures 
Author(s): Domingues, Marco M ; Bianconi, M Lucia ; Barbosa, Leandro RS ; [et al.] Source: BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES. Volume: 1828 Issue: 11 Pages: 2419-2427 DOI: 10.1016/j.bbamem.2013.06.009 Published: NOV 2013
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14.
Site-specific chemical modification of antibody fragments using traceless cleavable linkers
Author(s): Bernardes, Gonçalo JL ; Steiner, Martina ; Hartmann, Isabelle [et al.]. Source: NATURE PROTOCOLS Volume: 8 Issue: 11 Pages: 2079-2089 DOI: 10.1038/nprot.2013.121 Published: NOV 2013
Abstract

15.
Abuse liability measures for use in analgesic clinical trials in patients with pain: IMMPACT recommendations 
Author(s): O’Connor, Alec B. ; Turk, Dennis C ; Dworkin, Robert H. [et al.].
Source: PAIN. Volume: 154 Issue: 11 Pages: 2324-2334 DOI: 10.1016/j.pain.2013.06.035 Published: NOV 2013
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16.
Meanings of quality of care: Perspectives of Portuguese health professionals and patients
Author(s): Silva, Sílvia A ; Costa, Patrícia L ; Costa, Rita ; [et al.].
Source: BRITISH JOURNAL OF HEALTH PSYCHOLOGY Volume: 18 Issue: 4 Pages: 858-873 DOI: 10.1111/bjhp.12031 Published: NOV 2013
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17.
European consensus on the histopathology of inflammatory bowel disease
Author(s): Magro, F ; Langner, C ; Driessen, A [et al.] Group Author(s): ESP ; ECCO
Source: JOURNAL OF CROHNS & COLITIS Volume: 7 Issue: 10 Pages: 827-851 DOI: 10.1016/j.crohns.2013.06.001 Published: NOV 1 2013
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18.
Neuropeptide kyotorphin (tyrosyl-arginine) has decreased levels in the cerebro-spinal fluid of Alzheimer’s disease patients: potential diagnostic and pharmacologic alimplications
Author(s): Santos, Sara Matos ; Garcia Nimo, Laura ; Santos, Sónia Sá [et al.].
Source: FRONTIERS IN AGING NEUROSCIENCE Volume: 5 Article Number: UNSP 68 DOI: 10.3389/fnagi.2013.00068 Published: OCT 30 2013 Texto integral

19.
Chromosomal Contact Permits Transcription between Coregulated Genes 
Author(s): Fanucchi, Stephanie ; Shibayama, Youtaro ; Burd, Shaun [et al.] Source: CELL Volume: 155 Issue: 3 Pages: 606-620 Published: OCT 24 2013
Abstract

20.
Non-compaction cardiomyopathy
Author(s): Almeida, Ana G ; Pinto, Fausto J.
Source: HEART Volume: 99 Issue: 20 Pages: 1535-1542 DOI: 10.1136/heartjnl-2012-302048 Published: OCT 15 2013
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21.
The Antimicrobial Activity of Sub3 is Dependent on Membrane Binding and Cell-Penetrating Ability 
Author(s): Torcato, Inês M ; Huang, Yen-Hua ; Franquelim, Henri G [et al.].
Source: CHEMBIOCHEM. Volume: 14 Issue: 15 Pages: 2013-2022 DOI: 10.1002/cbic.201300274 Published: OCT 11 2013
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22.
Structural Optimization of Quinolon-4(1H)-imines as Dual-Stage Antimalarials: Toward Increased Potency and Metabolic Stability
Author(s): Ressurreição, Ana S ; Gonçalves, Daniel ; Sitoe, Ana R
Source: JOURNAL OF MEDICINAL CHEMISTRY. Volume: 56 Issue: 19
Pages: 7679-7690 Published: OCT 10 2013
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23.
The NAD-dependent deacetylase sirtuin 2 is a suppressor of microglial activation and brain inflammation 
Author(s): Pais, Teresa Faria ; Szego, Eva M ; Marques, Oldriska [et al.] Source: EMBO JOURNAL Volume: 32 Issue: 19 Pages: 2603-2616 DOI: 10.1038/emboj.2013.200 Published: OCT 2 2013
Abstract

24.
Caffeine does not increase the risk of atrial fibrillation: a systematic review and meta-analysis of observational studies 
Author(s): Caldeira, Daniel ; Martins, Cristina ; Alves, Luís Brandão
Source: HEART Volume: 99 Issue: 19 Pages: 1383-1389 DOI: 10.1136/heartjnl-2013-303950 Published: OCT 1 2013
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25.
Association of metabolic risk factors with uncontrolled hypertension: comparison of the several definitions of metabolic syndrome 
Author(s): Cortez Dias, Nuno ; Martins, Susana R ; Belo, Adriana
Group Author(s): VALSIM Study Investigators.
Source: JOURNAL OF HYPERTENSION. Volume: 31 Issue: 10 Pages: 1991-1997 Published: OCT 2013
Abstract

26.
The hemozoin conundrum: is malaria pigment immune-activating, inhibiting, or simply a bystander?
Author(s): Boura, Márcia ; Frita, Rosangela ; Góis, Ana.
Source: TRENDS IN PARASITOLOGY Volume: 29 Issue: 10 Pages: 469-476 DOI: 10.1016/j.pt.2013.07.005 Published: OCT 2013
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27.
Quantitative Wearable Sensors for Objective Assessment of Parkinson’s Disease
Author(s): Maetzler, Walter ; Domingos, Josefa ; Srulijes, Karin ; Ferreira, Joaquim J. ; Bloem, Bastiaan R.
Source: MOVEMENT DISORDERS Volume: 28 Issue: 12 Pages: 1628-1637 DOI: 10.1002/mds.25628 Published: OCT 2013
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28.
Tissue Doppler Imaging and Plasma N-Terminal Probrain Natriuretic Peptide for the Identification of Hypertrophic Cardiomyopathy Mutation Carriers 
Author(s): Silva, Doroteia ; Madeira, Hugo ; Almeida, Augusto ; Brito, Dulce.
Source: AMERICAN JOURNAL OF CARDIOLOGY Volume: 112 Issue: 7 Pages: 996-1004 DOI: 10.1016/j.amjcard.2013.05.039 Published: OCT 1 2013
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29.
Kinetic uptake profiles of cell penetrating peptides in lymphocytes and monocytes 
Author(s): Rodrigues, Margarida ; de la Torre, Beatriz G ; Andreu, David ; Santos, Nuno C.
Source: BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS Volume: 1830 Issue: 10 Pages: 4554-4563 DOI: 10.1016/j.bbagen.2013.05.020 Published: OCT 2013
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